In accordance with the needs of the personalized medical service industry such as dentures, combined with Internet+, smart manufacturing, digital medical devices, industrial robots, 3D printing, big data, 3D visualization and other technologies, GRIMI has established the first denture Internet+personalized medical intelligent manufacturing system which including the interaction platform among companies, doctors, and patients, manufacturing and execution system, intelligent logistics system, and enterprise management information system. It has digitally upgraded traditional medical care, realized the information communication between doctors and patients, and created a new personalized medical business model and new health service model.